Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460117 | 1.00 | MET (0.55) | METNQO2HDAC1 | |
| SCHEMBL2456716 | 0.87 | MET (0.64) | METNQO2 | |
| SCHEMBL15428449 | 0.87 | MET (0.60) | METNQO2 | |
| SCHEMBL2528788 | 0.86 | MET (0.54) | METNQO2 | |
| SCHEMBL2528792 | 0.86 | MET (0.54) | METNQO2 | |
| SCHEMBL12239820 | 0.83 | MET (0.57) | METNQO2HDAC1 | |
| SCHEMBL3084139 | 0.83 | MET (0.64) | METNQO2 | |
| SCHEMBL3088599 | 0.82 | MET (0.76) | METNQO2 | |
| SCHEMBL2455862 | 0.82 | MET (0.63) | METNQO2HDAC1 | |
| SCHEMBL2526060 | 0.82 | MET (0.56) | METNQO2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637518-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2014-01-28 | — | — | US | claimed |