SCHEMBL15428801

SCHEMBL15428801

CC(C)OC(=O)/C=C/C=C/c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
AKR1B10 O60218 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
AKR1B1 P15121 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC7 Q8WUI4 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC10 Q969S8 2/20 0.53
HDAC11 Q96DB2 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
HDAC9 Q9UKV0 2/20 0.53
HDAC5 Q9UQL6 2/20 0.53
CYP1A2 P05177 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Cinnamate SCHEMBL133104 0.88 AKR1B10 (0.72) CA12AKR1B10CA1CA2AKR1B1
Isopropyl Cinnamate SCHEMBL133105 0.88 AKR1B10 (0.72) CA12AKR1B10CA1CA2AKR1B1
Isopropyl Cinnamate SCHEMBL11996898 0.88 AKR1B10 (0.72) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL10895249 0.87 HDAC3 (0.50) CA12AKR1B10CA1CA2AKR1B1
Isopropyl Cinnamate SCHEMBL28009788 0.86 AKR1B10 (0.70) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL15163756 0.84 MEN1 (0.49) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL14356149 0.84 MEN1 (0.49) CA12AKR1B10CA1CA2AKR1B1
Cinnamic Acid SCHEMBL16735424 0.83 HCAR2 (0.63) CA12AKR1B10CA1CA2AKR1B1
Cinnamic Acid SCHEMBL16735425 0.83 HCAR2 (0.63) CA12AKR1B10CA1CA2AKR1B1
SCHEMBL20244541 0.83 MEN1 (0.48) CA12AKR1B10CA1CA2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014011935-A1 COATING MATERIALS FOR OXIDE THIN FILM TRANSISTORS POLYERA CORPORATION (US) 2014-01-16 WO disclosed