SCHEMBL15430220

SCHEMBL15430220

c1ccc2c(c1)sc1c(-c3ccc(-c4ccc5c(c4)c4ccccc4c4nccn54)cc3)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
PRKDC P78527 5/20 0.37
PARP14 Q460N5 1/20 0.35
ADK P55263 1/20 0.35
LIMK1 P53667 2/20 0.33
DNPH1 O43598 1/20 0.32
PIK3CD O00329 2/20 0.31
PIK3CB P42338 2/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
TACR1 P25103 1/20 0.30
HTT P42858 1/20 0.30
PAX8 Q06710 1/20 0.30
PIM3 Q86V86 1/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15430223 1.00 ALOX5 (0.44) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430225 0.98 ALOX5 (0.43) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430224 0.96 ALOX5 (0.40) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430222 0.96 ALOX5 (0.46) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430227 0.96 ALOX5 (0.47) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15405596 0.95 ALOX5 (0.46) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15405088 0.95 ALOX5 (0.46) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430240 0.93 ALOX5 (0.45) ALOX5PRKDCPARP14ADKDNPH1
SCHEMBL15430228 0.93 ALOX5 (0.46) ALOX5PRKDCPARP14ADKLIMK1
SCHEMBL15430239 0.92 ALOX5 (0.44) ALOX5PRKDCPARP14ADKDNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed