SCHEMBL15430366

SCHEMBL15430366

Cc1cc(-c2ccc3c(c2)c2ccccc2c2nccn32)ccc1-c1ccc(-c2cccc3c2oc2ccccc23)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
GGPS1 O95749 1/20 0.36
PRKDC P78527 6/20 0.36
PTGES2 Q9H7Z7 1/20 0.34
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
DRD1 P21728 3/20 0.31
CA12 O43570 3/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA9 Q16790 3/20 0.31
ADK P55263 1/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
FLT1 P17948 1/20 0.30
CDK8 P49336 1/20 0.30
CDK9 P50750 1/20 0.30
LIMK1 P53667 1/20 0.30
ROCK1 Q13464 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23866422 0.92 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430354 0.91 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430305 0.91 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430298 0.91 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430304 0.90 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430297 0.90 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430303 0.90 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430313 0.89 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430311 0.89 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2PRMT5
SCHEMBL15430306 0.89 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed
US-20140014930-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-01-16 US disclosed