Gentiopicroside

Gentiopicroside

SCHEMBL154304

C=C[C@@H]1C2=CCOC(=O)C2=CO[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 8/20 0.58
PTPN1 P18031 5/20 0.43
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gentiopicroside SCHEMBL31387950 1.00 STAT3 (0.58) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL29655354 0.95 STAT3 (0.54) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL30486432 0.94 STAT3 (0.53) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL28586772 0.84 STAT3 (0.48) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL29655381 0.81 HSP90AA1 (0.48) STAT3PTPN1
SCHEMBL29391780 0.74 STAT3 (0.38) STAT3PTPN1MAPTMEN1KMT2A
Sweroside SCHEMBL307117 0.73 STAT3 (1.00) STAT3PTPN1MAPTMEN1KMT2A
Sweroside SCHEMBL14278967 0.73 STAT3 (1.00) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL28267368 0.71 STAT3 (0.72) STAT3PTPN1MAPTMEN1KMT2A
SCHEMBL29392885 0.71 STAT3 (0.51) STAT3PTPN1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3093 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122042884-A Quality detection method of liver-purging and nerve-soothing capsules 成都倍特得诺药业有限公司 2026-05-15 CN claimed
CN-122005397-A Preparation method of high-activity gentian anti-inflammatory active component capable of relieving 广州精粹堂化妆品有限公司 2026-05-12 CN claimed
CN-121570407-A Umbilical cord blood water-light essence composition, umbilical cord blood water-light essence and preparation method and application thereof 广州森野生物医药科技有限公司 2026-02-27 CN claimed
EP-4650770-A1 METHOD FOR CONSTRUCTING CHICORY-PORIA COMPOUND FINGERPRINT, AND FINGERPRINT AND USE THEREOF Beijing University of Chinese Medicine (CN) 2025-11-19 EP claimed
EP-4304623-B1 FOOD SUPPLEMENT TO PROMOTE BODY WEIGHT LOSS NGN HEALTHCARE NEW GENERATION NUTRACEUTICALS S R L (IT) 2025-11-19 EP claimed
US-20250302794-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR THE TREATMENT OF CUTANEOUS DISORDERS VERRICA PHARMACEUTICALS INC. (US) 2025-10-02 US claimed
CN-120154557-A Acne-removing composition containing ceramide, preparation method thereof and acne-removing product 广州市比柔生物科技有限公司 2025-06-17 CN claimed
EP-4379068-B1 IRIDOID OR SECO-IRIDOID DERIVATIVES AND THEIR USE IN A TANNING PROCESS INSTITUT NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) 2025-06-04 EP claimed
CN-120084909-A Multi-component content determination method for four-ingredient Tibetan cat-milk soup 青岛科技大学 2025-06-03 CN claimed
CN-120064510-A Method for checking medicine for treating hearing loss 河北永丰药业有限公司 2025-05-30 CN claimed
CN-1590398-A Preparation of gentian effective part and its application HU SHAOYONG (CN) 2005-03-09 CN claimed
WO-2005004989-A2 FILM COMPRISING THERAPEUTIC AGENTS MAIBACH TODD (US) 2005-01-20 WO claimed
CN-1437953-A Gentiamarin powder infection for muscle injection and intravenous injection SU WEIJI (CN) 2003-08-27 CN claimed
CN-1403099-A Chinese medicine prepn for treating hepatosis and its prepn process LOU RUJU (CN) 2003-03-19 CN claimed
CN-1089243-C Medicine for promoting digestion function of stomach and intestine SUN WENJI (CN) 2002-08-21 CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1191132-A Medicine for promoting digestion function of stomach and intestine SUN WENJI (CN) 1998-08-26 CN claimed
US-5208151-A Process for the preparation of derivatives of maltooligosaccharides NIHON SHOKUHIN KAKO CO., LTD. (JP) 1993-05-04 US claimed