Sweroside

Sweroside

SCHEMBL14278967

C=C[C@H]1[C@H](O[C@@H]2OC(CO)[C@@H](O)[C@@H](O)C2O)OC=C2C(=O)OCC[C@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 9/20 1.00
MAPT P10636 2/20 0.42
PTPN1 P18031 6/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sweroside SCHEMBL307117 1.00 STAT3 (1.00) STAT3MAPTPTPN1MEN1KMT2A
SCHEMBL14305641 0.85 STAT3 (0.73) STAT3MAPTPTPN1MEN1KMT2A
SCHEMBL14534198 0.85 STAT3 (0.73) STAT3MAPTPTPN1MEN1KMT2A
SCHEMBL28267368 0.84 STAT3 (0.72) STAT3MAPTPTPN1MEN1KMT2A
SCHEMBL21807732 0.84 STAT3 (0.72) STAT3MAPTPTPN1MEN1KMT2A
SCHEMBL29425739 0.83 STAT3 (0.69) STAT3PTPN1MEN1KMT2A
SCHEMBL29655347 0.81 STAT3 (0.67) STAT3PTPN1
SCHEMBL29471040 0.81 STAT3 (0.68) STAT3MAPT
SCHEMBL29471039 0.81 STAT3 (0.68) STAT3MAPT
SCHEMBL29426226 0.80 STAT3 (0.64) STAT3MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314644-B2 Extraction and purification method of active constituents from stem of Lonicera japonica thunb., its usage for anti-inflammatory and analgesic drug SK CHEMICALS CO., LTD. (KR) 2008-01-01 US disclosed
US-20070111955-A1 Extraction and purification method of active constituents from stem of Lonicera japonica Thunb., its usage for anti-inflammatory and analgesic drug KWAK WIE-JONG 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070111955-A1 Extraction and purification method of active constituents from stem of Lonicera japonica Thunb., its usage for anti-inflammatory and analgesic drug SENP7, LONP1, SYMPK STAT3 785/4885MAPT 3260/4885PTPN1 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.