SCHEMBL15432172

SCHEMBL15432172

Cc1ccc(-c2cnc(-c3ccc(C)s3)cn2)s1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.48
MAPT P10636 4/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GFER P55789 1/20 0.48
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
RAB9A P51151 4/20 0.37
KDM4E B2RXH2 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14479821 0.91 ALDH1A1 (0.42) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL12405064 0.81 NPC1 (0.42) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL23665366 0.81 CCR1 (0.62) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL29764 0.80 NPC1 (0.52) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL13416007 0.80 HTT (0.45) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL24970240 0.78 MAPT (0.40) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL12170048 0.77 NPC1 (0.50) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL12982161 0.77 NPC1 (0.50) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL120939 0.77 NPC1 (0.50) NPC1MAPTALDH1A1HSD17B10GFER
SCHEMBL12982405 0.77 NPC1 (0.50) NPC1MAPTALDH1A1HSD17B10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed