Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692100 | 0.86 | HPGD (0.49) | HPGDMEN1KMT2AMAPTPKM | |
| SCHEMBL2107971 | 0.83 | NAMPT (0.48) | IL2RAB9A | |
| SCHEMBL1043517 | 0.83 | KDM4C (0.46) | MEN1KMT2AMAPTPKMIL2 | |
| SCHEMBL4139383 | 0.81 | ALDH1A1 (0.55) | HPGDMEN1KMT2AIL2CHUK | |
| SCHEMBL360914 | 0.81 | KMT2A (0.51) | HPGDMEN1KMT2AMAPTKDM4E | |
| SCHEMBL15432244 | 0.81 | KDM4E (0.56) | HPGDMEN1KMT2AMAPTCHUK | |
| SCHEMBL1128597 | 0.81 | BCHE (0.49) | HPGDMEN1KMT2AMAPTPKM | |
| SCHEMBL17655428 | 0.80 | SIRT3 (0.50) | HPGDKMT2AMAPTPKMIL2 | |
| SCHEMBL5455954 | 0.79 | ALDH1A1 (0.42) | KMT2AMAPTIL2KDM4EALDH1A1 | |
| SCHEMBL15432248 | 0.77 | KDM4E (0.51) | HPGDMEN1KMT2AMAPTCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024621-A1 | AMINOPYRIDINE COMPOUNDS AND THEIR USES | MS THERAPEUTICS LIMITED (GB) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024621-A1 | AMINOPYRIDINE COMPOUNDS AND THEIR USES | DNPEP, PEPD, ANPEP | HPGD 320/4885MEN1 2266/4885KMT2A 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.