SCHEMBL15433174

SCHEMBL15433174

FC(F)=C(F)c1ccc(-c2ccc(-c3cc(F)c(F)c(F)c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 13/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ERN1 O75460 2/20 0.37
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
KIF11 P52732 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433380 1.00 ANPEP (0.39) ANPEPKDM4ELMNAHSD17B10CES2
SCHEMBL15433484 0.89 CYP17A1 (0.38) ANPEPKDM4ELMNAHSD17B10KIF11
SCHEMBL15433252 0.89 CYP17A1 (0.38) ANPEPKDM4ELMNAHSD17B10KIF11
SCHEMBL15433171 0.87 KDM4E (0.38) ANPEPKDM4ELMNAHSD17B10CES2
SCHEMBL15433409 0.87 NPC1 (0.44) ANPEPKDM4ELMNAHSD17B10
SCHEMBL15433180 0.86 RARB (0.36) ANPEPKDM4ELMNAHSD17B10CES2
SCHEMBL15433829 0.86 ESR1 (0.38) ANPEPKDM4ELMNAHSD17B10ESR1
SCHEMBL15433390 0.85 CES2 (0.36) ANPEPKDM4ELMNAHSD17B10CES2
SCHEMBL15433176 0.84 ANPEP (0.41) ANPEPKDM4ELMNAHSD17B10ERN1
SCHEMBL15433210 0.84 ESR1 (0.39) KDM4ELMNAHSD17B10ERN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed