SCHEMBL15433254

SCHEMBL15433254

CC/C(F)=C(\F)c1ccc(CCc2ccc(-c3cc(F)c(F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.41
MAOB P27338 1/20 0.32
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
KDM1A O60341 1/20 0.31
MPL P40238 2/20 0.31
RARA P10276 1/20 0.30
RARG P13631 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433495 0.95 RARB (0.38) RARBS1PR1S1PR3MPL
SCHEMBL7239283 0.87 MAOB (0.37) RARBMAOBS1PR1
SCHEMBL7239274 0.87 MAOB (0.37) RARBMAOBS1PR1
SCHEMBL7239279 0.87 MAOB (0.37) RARBMAOBS1PR1
SCHEMBL15433488 0.87 RARB (0.38) RARBMAOBS1PR1S1PR3KDM1A
SCHEMBL15433538 0.86 RARB (0.38) RARBMAOBRARARARG
SCHEMBL15433179 0.86 RARB (0.36) RARB
SCHEMBL15433387 0.86 RARB (0.36) RARB
SCHEMBL15433170 0.86 RARB (0.36) RARB
SCHEMBL15433607 0.85 RARB (0.38) RARBS1PR1S1PR3KDM1ARARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed