SCHEMBL15433387

SCHEMBL15433387

CC/C(F)=C(\F)c1ccc(-c2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.36
ANPEP P15144 3/20 0.34
KIF11 P52732 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
MGLL Q99685 1/20 0.32
CYP3A4 P08684 2/20 0.31
CYP17A1 P05093 2/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
ESR1 P03372 3/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433170 1.00 RARB (0.36) RARBANPEPKIF11KDM4ELMNA
SCHEMBL15433179 1.00 RARB (0.36) RARBANPEPKIF11KDM4ELMNA
SCHEMBL15433831 0.95 RARB (0.33) RARBANPEPKIF11KDM4ELMNA
SCHEMBL15433395 0.92 ANPEP (0.34) RARBANPEPAKR1C3AKR1C2CYP3A4
SCHEMBL15433181 0.90 RARB (0.40) RARBANPEPCYP3A4ESR1ALDH1A1
SCHEMBL15433182 0.89 ANPEP (0.40) ANPEPKIF11KDM4ELMNAHSD17B10
SCHEMBL15433383 0.89 ANPEP (0.40) ANPEPKIF11KDM4ELMNAHSD17B10
SCHEMBL15433254 0.86 RARB (0.41) RARB
SCHEMBL15433215 0.86 KIF11 (0.39) RARBKIF11KDM4ELMNAHSD17B10
SCHEMBL15433429 0.85 KIF11 (0.38) RARBKIF11AKR1C3AKR1C2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed