SCHEMBL15433374

SCHEMBL15433374

CCC/C(F)=C(\F)c1ccc(C2CCC(OCc3cc(F)c(C(F)F)c(F)c3)CC2)cc1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESRRB O95718 2/20 0.33
ESR1 P03372 2/20 0.33
ESRRG P62508 2/20 0.33
KCNH2 Q12809 2/20 0.33
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433192 0.74 CYP2C9 (0.38) ESRRBESR1ESRRGKCNH2CYP2C9
SCHEMBL15433217 0.71 CYP2C9 (0.38) CYP2C9
SCHEMBL7230477 0.69 CYP2C9 (0.59) ESR1CYP2C9
SCHEMBL7229613 0.67 CYP2C9 (0.56) ESR1CYP2C9
SCHEMBL8433784 0.67 CYP2C9 (0.56) ESR1CYP2C9
SCHEMBL7230281 0.66 CYP2C9 (0.45) CYP2C9
SCHEMBL7766038 0.66 CYP2C9 (0.45) CYP2C9
SCHEMBL7230277 0.66 CYP2C9 (0.45) CYP2C9
SCHEMBL7230123 0.65 SPHK1 (0.36) CYP2C9
SCHEMBL7765117 0.65 SPHK1 (0.36) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed