SCHEMBL15433507

SCHEMBL15433507

CCCC/C(F)=C(\F)c1ccc(CCc2ccc(-c3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.41
S1PR1 P21453 3/20 0.37
S1PR3 Q99500 2/20 0.37
RORC P51449 1/20 0.33
KDM1A O60341 10/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
PPARD Q03181 1/20 0.33
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433590 0.93 RARB (0.37) RARBS1PR1S1PR3RORCKDM1A
SCHEMBL15433510 0.91 RARB (0.41) RARBS1PR1S1PR3RORCFFAR1
SCHEMBL15433722 0.86 RARB (0.36) RARBS1PR1S1PR3RORCFFAR1
SCHEMBL15433587 0.85 RARB (0.32) RARBKDM1AFFAR1FFAR4
SCHEMBL15433726 0.83 RARB (0.32) RARBKDM1AFFAR1FFAR4
SCHEMBL15433266 0.83 FFAR1 (0.31) KDM1AFFAR1FFAR4
SCHEMBL15433728 0.82 RARB (0.35) RARBS1PR1S1PR3RORCFFAR4
SCHEMBL15433816 0.82 S1PR1 (0.34) RARBS1PR1S1PR3FFAR1FFAR4
SCHEMBL15433592 0.81 RARB (0.35) RARBS1PR1S1PR3KDM1AFFAR4
SCHEMBL7231512 0.81 RARB (0.51) RARBS1PR1S1PR3RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed