SCHEMBL15433587

SCHEMBL15433587

C/C=C/CC/C(F)=C(\F)c1ccc(-c2ccc(CCc3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.32
KDM1A O60341 11/20 0.32
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433266 0.87 FFAR1 (0.31) KDM1AFFAR1FFAR4
SCHEMBL15433316 0.86 FFAR4 (0.31) FFAR4
SCHEMBL15433262 0.85 RARB (0.32) RARB
SCHEMBL15433507 0.85 RARB (0.41) RARBKDM1AFFAR1FFAR4
SCHEMBL15433658 0.83 FFAR4 (0.33) FFAR1FFAR4
SCHEMBL13239290 0.83 GRM2 (0.34) RARBFFAR1FFAR4
SCHEMBL13412057 0.83 ALOX5AP (0.34) KDM1AFFAR1FFAR4
SCHEMBL13412058 0.83 GRM2 (0.34) RARBFFAR1FFAR4
SCHEMBL15433589 0.82 RARB (0.33) RARBKDM1AFFAR1FFAR4
SCHEMBL15433504 0.82 RARB (0.30) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed