SCHEMBL15433576

SCHEMBL15433576

CCO/C(F)=C(\F)c1ccc(-c2ccc(CCc3ccc(-c4cc(F)c(C(F)(F)F)c(F)c4)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.34
PPARD Q03181 2/20 0.34
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433499 0.91 RARB (0.37) RARBPPARDS1PR1S1PR3
SCHEMBL15433502 0.87 RARB (0.34) RARBPPARD
SCHEMBL15433263 0.86
SCHEMBL15433307 0.85 PPARD (0.30) PPARD
SCHEMBL15433833 0.83 PDK2 (0.37) RARBPPARD
SCHEMBL15433591 0.83 RARB (0.31) RARBS1PR1S1PR3
SCHEMBL15433494 0.82 RARB (0.33) RARB
SCHEMBL15433214 0.82 PDK2 (0.38) RARBPPARD
SCHEMBL15433573 0.81 RARB (0.34) RARBPPARDS1PR1S1PR3
SCHEMBL15433673 0.81 RARB (0.39) RARBPPARDS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed