SCHEMBL15433833

SCHEMBL15433833

CCO/C(F)=C(\F)c1ccc(-c2ccc(-c3ccc(-c4ccc(-c5cc(F)c(C(F)(F)F)c(F)c5)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.37
KIF11 P52732 3/20 0.36
PPARD Q03181 3/20 0.33
AKR1C3 P42330 3/20 0.33
AKR1C2 P52895 3/20 0.33
AKR1B10 O60218 1/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C1 Q04828 1/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
APP P05067 1/20 0.32
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
RARB P10826 1/20 0.31
PTGS2 P35354 1/20 0.31
PRKCZ Q05513 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433214 0.99 PDK2 (0.38) PDK2KIF11PPARDAKR1C3AKR1C2
SCHEMBL15433793 0.90 PDK2 (0.33) PDK2KIF11PTGS2
SCHEMBL15433499 0.90 RARB (0.37) PDK2PPARDAKR1C3AKR1C2AKR1B10
SCHEMBL15433613 0.87 PDK2 (0.33) PDK2
SCHEMBL15433426 0.85 PDK2 (0.38) PDK2AKR1C3AKR1C2ALOX5APFEN1
SCHEMBL15433621 0.85 MAPT (0.37) PDK2KIF11PPARDRARBPRKCZ
SCHEMBL15433429 0.84 KIF11 (0.38) KIF11PPARDAKR1C3AKR1C2AKR1B10
SCHEMBL15433576 0.83 RARB (0.34) PPARDRARB
SCHEMBL15433466 0.83 AKR1C3 (0.35) PDK2AKR1C3AKR1C2APPRARB
SCHEMBL15433215 0.83 KIF11 (0.39) PDK2KIF11PPARDAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed