Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434147 | 0.83 | FFAR4 (0.49) | FFAR1FFAR4EPHX2PPARGPPARA | |
| SCHEMBL20639049 | 0.81 | FFAR1 (0.47) | FFAR1FFAR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL584599 | 0.78 | FFAR1 (0.64) | FFAR1FFAR4PLA2G4A | |
| SCHEMBL15434106 | 0.77 | FFAR1 (0.48) | FFAR1FFAR4SLC6A2SLC6A4PPARG | |
| SCHEMBL2537453 | 0.77 | FFAR1 (0.48) | FFAR1FFAR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30784592 | 0.77 | FFAR1 (0.48) | FFAR1FFAR4TRPV1 | |
| SCHEMBL20641751 | 0.74 | SLC6A2 (0.44) | FFAR1FFAR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1123025 | 0.74 | FFAR1 (0.67) | FFAR1FFAR4PLA2G4A | |
| SCHEMBL9138435 | 0.74 | CTNNB1 (0.51) | SLC6A2SLC6A4SLC6A3EPHX2LTA4H | |
| SCHEMBL15429152 | 0.73 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |