Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15429148 | 0.85 | SLC6A2 (0.41) | FFAR4FFAR1NPSR1NR1H4EPHX2 | |
| SCHEMBL15434126 | 0.83 | FFAR1 (0.48) | FFAR4FFAR1LTB4REPHX2TRPV1 | |
| SCHEMBL13580818 | 0.82 | TRPV1 (0.43) | FFAR4FFAR1NPSR1NR1H4EPHX2 | |
| SCHEMBL15434115 | 0.80 | FFAR4 (0.53) | FFAR4FFAR1NPSR1PPARGPPARA | |
| SCHEMBL15434111 | 0.80 | NPSR1 (0.47) | FFAR4FFAR1NPSR1NR1H4EPHX2 | |
| SCHEMBL15434180 | 0.80 | NPSR1 (0.47) | FFAR4FFAR1NPSR1NR1H4EPHX2 | |
| SCHEMBL2536068 | 0.80 | FFAR1 (0.46) | FFAR4FFAR1NPSR1NR1H4EPHX2 | |
| SCHEMBL15434130 | 0.78 | FFAR1 (0.51) | FFAR4FFAR1NPSR1PPARGPPARA | |
| SCHEMBL15434148 | 0.78 | TRPV1 (0.41) | FFAR4NPSR1NR1H4EPHX2TRPV1 | |
| SCHEMBL15434125 | 0.77 | FFAR1 (0.47) | FFAR4FFAR1NPSR1NR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |