Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434157 | 0.88 | NPSR1 (0.51) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434130 | 0.88 | FFAR1 (0.51) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434111 | 0.85 | NPSR1 (0.47) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434180 | 0.85 | NPSR1 (0.47) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434119 | 0.84 | NPSR1 (0.51) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434104 | 0.83 | PPARG (0.49) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434163 | 0.83 | PPARG (0.48) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434113 | 0.82 | PPARG (0.44) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434094 | 0.82 | FFAR4 (0.51) | FFAR1PPARGPPARAPPARDNPSR1 | |
| SCHEMBL15434146 | 0.81 | PPARG (0.45) | FFAR1PPARGPPARAPPARDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |