Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997669 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL15429219 | 0.89 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL5535254 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1KDM4EDUSP3 | |
| SCHEMBL347487 | 0.87 | TSHR (0.61) | TSHRTHRBALDH1A1KDM4EDUSP3 | |
| SCHEMBL651673 | 0.86 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| Ethylene Glycol SCHEMBL11168150 | 0.85 | TSHR (0.55) | TSHRTHRBALDH1A1KDM4EDUSP3 | |
| SCHEMBL7032638 | 0.85 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL18492491 | 0.85 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL13896955 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL18660130 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9823210-B2 | Method of manufacturing a biosensor | STMICROELECTRONICS S.R.L. (IT) | 2017-11-21 | — | — | US | disclosed |
| US-20160157764-A1 | MICRONEEDLE ARRAY DEVICE AND METHOD OF MAKING | STMICROELECTRONICS S.R.L. (IT) | 2016-06-09 | — | — | US | disclosed |
| US-9244067-B2 | Biosensor | STMICROELECTRONICS S.R.L. (IT) | 2016-01-26 | — | — | US | disclosed |
| US-20140017772-A1 | BIOSENSOR | STMICROELECTRONICS INTERNATIONAL N.V. (CH) | 2014-01-16 | — | — | US | disclosed |