SCHEMBL651673

SCHEMBL651673

C=C(C)C(=O)OCC(O)COCC(CC)OCC(O)COC(=O)C(=C)C

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL997669 0.92 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL15434293 0.86 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL5535254 0.85 TSHR (0.61) TSHRTHRBALDH1A1
SCHEMBL347487 0.85 TSHR (0.61) TSHRTHRBALDH1A1
SCHEMBL15429219 0.85 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL18660130 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL7032296 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL13896955 0.83 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL996250 0.81 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL11306460 0.81 TSHR (0.53) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504448-B2 High-impact, transparent prosthesis material having a low residual MMA content KULZER GMBH (DE) 2022-11-22 US disclosed
EP-3164097-B1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL KULZER & CO GMBH (DE) 2022-05-11 EP disclosed
US-11007302-B2 Auto-polymerizable prosthetic material and polymerized, fracture-tough prosthetic material with increased colour stability KULZER GMBH (DE) 2021-05-18 US disclosed
US-20200289705-A1 HIGH-IMPACT, TRANSPARENT PROSTHESIS MATERIAL HAVING A LOW RESIDUAL MMA CONTENT KULZER GMBH (DE) 2020-09-17 US disclosed
EP-3373991-B1 HIGH-IMPACT, TRANSPARENT PROSTHESIS MATERIAL HAVING A LOW RESIDUAL MMA CONTENT KULZER & CO GMBH (DE) 2020-07-01 EP disclosed
US-20200071513-A1 Curable (meth)acrylic resin compositions having enhanced viscosity RÖHM GMBH (DE) 2020-03-05 US disclosed
EP-2529762-B1 PROSTHETIC BASE MATERIAL THAT IS BREAK-RESISTANT AFTER HARDENING, DERIVED FROM AUTOPOLYMERISING OR COLD POLYMERISING COMPOUNDS KULZER & CO GMBH (DE) 2019-10-16 EP disclosed
US-10420712-B2 Mill blanks based on a polymerized, fracture-tough prosthesis material HERAEUS KULZER GMBH (DE) 2019-09-24 US disclosed
US-10358552-B2 Impact-resistant molding material having an improved characteristics profile EVONIK RÖHM GMBH (DE) 2019-07-23 US disclosed
EP-3369788-B1 CURABLE THERMOSETTING RESIN COMPOSITIONS WITH IMPROVED MECHANICAL PROPERTIES EVONIK ROEHM GMBH (DE) 2019-05-08 EP disclosed
US-5408022-A Useful for dental materials, non-releasing antimicrobial polymer; addition polymers KURARAY CO., LTD. (JP) 1995-04-18 US disclosed
US-5350782-A Mixture of inorganic oxide particles of two sizes, addition polymerizable monomer KANEBO, LTD. (JP) 1994-09-27 US disclosed
US-5321053-A Curable mixture of vinyl monomer containing acidic group and photoinitiator KURARAY CO., LTD. (JP) 1994-06-14 US disclosed
EP-0537774-A1 Antimicrobial polymerizable composition, the polymer and article obtained from the same KURARAY CO., LTD. (JP) 1993-04-21 EP disclosed
EP-0530926-A1 Dental filling composition KANEBO LTD. (JP) 1993-03-10 EP disclosed
EP-0155812-B1 DENTAL COMPOSITIONS KURARAY CO., LTD. (JP) 1991-09-11 EP disclosed
EP-0150952-B1 PHOTOPOLYMERIZABLE COMPOSITION KURARAY CO., LTD. (JP) 1989-08-30 EP disclosed
US-4668712-A MONOMER, PHOTOINITIATOR, DENTAL FILLINGS KURARAY CO., LTD. (JP) 1987-05-26 US disclosed
EP-0150952-A2 Photopolymerizable composition KURARAY CO., LTD. (JP) 1985-08-07 EP disclosed
US-4302381-A Dental material KURARAY CO., LTD. (JP) 1981-11-24 US disclosed