Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16940028 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL15434663 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL21147462 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL19686996 | 0.83 | TDP1 (0.49) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL19407910 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL15434556 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL12463688 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL15434630 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL25056681 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 | |
| SCHEMBL16940044 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1TDP1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014012081-A2 | CHIRAL CONTROL | ONTORII, INC. (US) | 2014-01-16 | — | — | WO | disclosed |