Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148459 | 0.80 | TDP1 (0.43) | TDP1ALDH1A1CTSBLMNAPARP1 | |
| SCHEMBL15434759 | 0.78 | PDE7A (0.39) | TDP1ALDH1A1P2RX4PDE7APOLB | |
| SCHEMBL29442065 | 0.72 | TDP1 (0.50) | TDP1ALDH1A1CTSBLMNAKMT2A | |
| SCHEMBL869478 | 0.72 | TDP1 (0.50) | TDP1ALDH1A1CTSBLMNAKMT2A | |
| SCHEMBL15892940 | 0.72 | KDM4E (0.52) | TDP1ALDH1A1LMNAPARP1KMT2A | |
| SCHEMBL22833914 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CTSBLMNAKMT2ACYP3A4 | |
| SCHEMBL29470129 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CTSBLMNAKMT2ACYP3A4 | |
| SCHEMBL25241214 | 0.71 | KDM4E (0.41) | ALDH1A1P2RX4LMNACA2CA9 | |
| SCHEMBL25277587 | 0.70 | KDM4E (0.42) | ALDH1A1CYP1A2KDM4ECYP2C19PDE7A | |
| SCHEMBL28351422 | 0.70 | KDM4E (0.48) | ALDH1A1P2RX4LMNAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872589-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-20150295186-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-15 | — | — | US | disclosed |
| US-20150295186-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-15 | — | — | US | disclosed |
| WO-2014008967-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150295186-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EPCAM, OR10J3 | TDP1 1898/4885ALDH1A1 108/4885P2RX4 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.