Sugi Predict

Sugi Predict / Compounds / SCHEMBL15435208

SCHEMBL15435208

SCHEMBL15435208

Nc1ccc(CCCC2CCCC2)cc1F

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MOGAT2 Q3SYC2 6/20 0.39
▸ BCHE P06276 1/20 0.37
▸ SIGMAR1 Q99720 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ SLC18A3 Q16572 1/20 0.36
▸ SKP2 Q13309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15400513 0.94 ALDH1A1 (0.38) MOGAT2ALDH1A1SKP2
SCHEMBL15399734 0.90 SLC6A2 (0.39) ALDH1A1
SCHEMBL15399768 0.89 DAO (0.39) ALDH1A1
SCHEMBL15400462 0.87 MOGAT2 (0.39) MOGAT2ALDH1A1SKP2
SCHEMBL15400565 0.83 SLC6A2 (0.41) ALDH1A1
SCHEMBL15435368 0.81 SLC6A2 (0.43) MOGAT2BCHE
SCHEMBL17064316 0.81 SLC6A2 (0.39) SKP2
SCHEMBL6898427 0.80 MOGAT2 (0.39) MOGAT2BCHESIGMAR1SLC18A3
SCHEMBL12241634 0.77 ALDH1A1 (0.41) ALDH1A1
SCHEMBL8767290 0.76 ALDH1A1 (0.39) MOGAT2SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687507-B1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2016-03-09 — — EP disclosed
EP-2687507-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND Taisho Pharmaceutical Co., Ltd. (JP) 2014-01-22 — — EP disclosed