Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 10/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435378 | 0.91 | MOGAT2 (0.61) | MOGAT2ABCB1KMT2ATNFNOD2 | |
| SCHEMBL15435246 | 0.91 | MOGAT2 (0.77) | MOGAT2ABCB1 | |
| SCHEMBL15435212 | 0.89 | MOGAT2 (0.61) | MOGAT2ABCB1TNFNOD2NOD1 | |
| SCHEMBL16715492 | 0.89 | MOGAT2 (0.59) | MOGAT2ABCB1KMT2ATNFNOD2 | |
| SCHEMBL15435427 | 0.87 | MOGAT2 (0.63) | MOGAT2ABCB1KMT2ATNFNOD2 | |
| SCHEMBL15435300 | 0.86 | MOGAT2 (0.83) | MOGAT2ABCB1 | |
| SCHEMBL15435178 | 0.86 | MOGAT2 (0.65) | MOGAT2ABCB1KMT2ATNFNOD2 | |
| SCHEMBL15435279 | 0.86 | MOGAT2 (0.67) | MOGAT2 | |
| SCHEMBL15435247 | 0.85 | MOGAT2 (0.69) | MOGAT2ABCB1KMT2ATNFNOD2 | |
| SCHEMBL15435035 | 0.83 | MOGAT2 (0.63) | MOGAT2ABCB1KMT2ATNFNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |