Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 15/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435300 | 0.91 | MOGAT2 (0.83) | MOGAT2ABCB1 | |
| SCHEMBL15399493 | 0.90 | MOGAT2 (0.84) | MOGAT2 | |
| SCHEMBL16715476 | 0.89 | MOGAT2 (0.76) | MOGAT2 | |
| SCHEMBL15435427 | 0.88 | MOGAT2 (0.63) | MOGAT2ABCB1MEN1RAB9AKMT2A | |
| SCHEMBL15435212 | 0.88 | MOGAT2 (0.61) | MOGAT2ABCB1ACACBTNFNOD2 | |
| SCHEMBL15435195 | 0.88 | MOGAT2 (0.65) | MOGAT2 | |
| SCHEMBL15435227 | 0.87 | MOGAT2 (0.83) | MOGAT2ABCB1 | |
| SCHEMBL15435275 | 0.86 | MOGAT2 (0.59) | MOGAT2 | |
| SCHEMBL15435209 | 0.85 | MOGAT2 (0.63) | MOGAT2ABCB1MEN1KMT2ATNF | |
| SCHEMBL15435178 | 0.85 | MOGAT2 (0.65) | MOGAT2ABCB1ACACBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |