⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12583134 | 1.00 | — | — | |
| SCHEMBL12583504 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28008961 | 0.98 | GMNN (0.30) | — | |
| Hydrochloric Acid SCHEMBL28009022 | 0.98 | GMNN (0.30) | — | |
| Hydrochloric Acid SCHEMBL17560471 | 0.98 | GMNN (0.30) | — | |
| Hydrochloric Acid SCHEMBL28558421 | 0.98 | GMNN (0.30) | — | |
| Hydrochloric Acid SCHEMBL17560374 | 0.98 | GMNN (0.30) | — | |
| SCHEMBL30589710 | 0.88 | ROCK2 (0.32) | — | |
| SCHEMBL375244 | 0.80 | — | — | |
| SCHEMBL6106255 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087077-A | Thienopyrimidine and furopyrimidine derivative, its preparation method and application in medicines | SHANGHAI XIMAI MEDICAL TECHNOLOGY CO LTD | 2013-05-08 | — | — | CN | claimed |
| EP-0471592-B1 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | DOW CHEMICAL CO (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0552360-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-07-28 | — | — | EP | claimed |
| WO-1993003825-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| EP-0471592-A2 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | THE DOW CHEMICAL COMPANY (US) | 1992-02-19 | — | — | EP | claimed |
| CN-113396147-B | Aromatic heterocyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023205914-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2023-11-02 | — | — | WO | disclosed |
| CN-112703037-B | 5-to 7-membered heterocyclic amides as JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4119141-A1 | NELOTANSERIN FOR THE PROPHYLAXIS AND TREATMENT OF REM SLEEP BEHAVIOR DISORDER | Axovant Sciences GmbH (CH) | 2023-01-18 | — | — | EP | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-110382498-B | Fused imidazole-piperidine JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2022-07-12 | — | — | CN | disclosed |
| US-5447931-A | 6-Bromo-2-/4-methylpiperazinyl/pyridine and salts; drugs; treatment of disorders of serotoninergic system | SANOFI (FR) | 1995-09-05 | — | — | US | disclosed |
| EP-0471592-B1 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | DOW CHEMICAL CO (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0580465-A1 | New therapeutic use of heterocyclic piperazines as 5-HT3 agonists and new derivatives | SANOFI (FR) | 1994-01-26 | — | — | EP | disclosed |
| EP-0552360-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1993003825-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5167941-A | Sulfur dioxide; cationic polyelectrolyte stabilizers | THE DOW CHEMICAL COMPANY (US) | 1992-12-01 | — | — | US | disclosed |
| US-5098681-A | Piperaznes having carbonyl groups | THE DOW CHEMICAL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0471592-A2 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | THE DOW CHEMICAL COMPANY (US) | 1992-02-19 | — | — | EP | disclosed |