SCHEMBL15435374

SCHEMBL15435374

O=C(N1Cc2ccc(S(=O)(=O)Nc3ccc(F)cc3OCc3ccccc3)cc2C1)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MOGAT2 Q3SYC2 16/20 0.55
CYP19A1 P11511 2/20 0.46
MGAT2 Q10469 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15435266 0.87 MOGAT2 (0.70) MOGAT2
SCHEMBL15435149 0.86 MOGAT2 (0.60) MOGAT2
SCHEMBL16715426 0.86 MOGAT2 (0.71) MOGAT2
SCHEMBL16715435 0.84 MOGAT2 (0.69) MOGAT2
SCHEMBL15399883 0.83 MOGAT2 (0.81) MOGAT2
SCHEMBL16715425 0.81 MOGAT2 (0.65) MOGAT2MGAT2
SCHEMBL15435171 0.80 MOGAT2 (0.68) MOGAT2
SCHEMBL15435318 0.79 MOGAT2 (0.55) MOGAT2
SCHEMBL16715711 0.79 MOGAT2 (0.66) MOGAT2
SCHEMBL15435383 0.77 MOGAT2 (0.60) MOGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
EP-2687507-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND Taisho Pharmaceutical Co., Ltd. (JP) 2014-01-22 EP disclosed