Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 16/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435381 | 0.90 | MOGAT2 (0.67) | MOGAT2ALDH1A1ESR1ESR2LMNA | |
| SCHEMBL15435266 | 0.89 | MOGAT2 (0.70) | MOGAT2 | |
| SCHEMBL16715426 | 0.88 | MOGAT2 (0.71) | MOGAT2 | |
| SCHEMBL15435171 | 0.87 | MOGAT2 (0.68) | MOGAT2 | |
| SCHEMBL15435318 | 0.87 | MOGAT2 (0.55) | MOGAT2 | |
| SCHEMBL16715425 | 0.86 | MOGAT2 (0.65) | MOGAT2 | |
| SCHEMBL15435319 | 0.86 | MOGAT2 (0.69) | MOGAT2ESR1ESR2LMNA | |
| SCHEMBL16715711 | 0.85 | MOGAT2 (0.66) | MOGAT2 | |
| SCHEMBL15435383 | 0.84 | MOGAT2 (0.60) | MOGAT2 | |
| SCHEMBL15435374 | 0.84 | MOGAT2 (0.55) | MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |