Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16715435 | 0.90 | MOGAT2 (0.69) | MOGAT2LMNAESR1ESR2ALDH1A1 | |
| SCHEMBL15435267 | 0.90 | MOGAT2 (0.69) | MOGAT2ESR1ESR2 | |
| SCHEMBL16715439 | 0.85 | MOGAT2 (0.58) | MOGAT2ESR1ESR2 | |
| SCHEMBL25825941 | 0.81 | ESR1 (0.80) | ESR1ESR2SLC6A9 | |
| SCHEMBL15435224 | 0.81 | MOGAT2 (1.00) | MOGAT2 | |
| SCHEMBL15435319 | 0.80 | MOGAT2 (0.69) | MOGAT2LMNAESR1ESR2 | |
| SCHEMBL15435266 | 0.80 | MOGAT2 (0.70) | MOGAT2 | |
| SCHEMBL15435171 | 0.79 | MOGAT2 (0.68) | MOGAT2 | |
| SCHEMBL15435318 | 0.78 | MOGAT2 (0.55) | MOGAT2KMT2AMEN1 | |
| SCHEMBL16715426 | 0.78 | MOGAT2 (0.71) | MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |