Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22781212 | 0.71 | — | — | |
| SCHEMBL9294037 | 0.68 | ESR2 (0.37) | — | |
| SCHEMBL12019012 | 0.68 | TLR4 (0.40) | — | |
| SCHEMBL15468603 | 0.66 | MEN1 (0.38) | — | |
| SCHEMBL13770208 | 0.64 | CA1 (0.35) | — | |
| SCHEMBL25567352 | 0.62 | CA1 (0.31) | — | |
| SCHEMBL13985232 | 0.62 | — | — | |
| SCHEMBL13366336 | 0.62 | SLC18A3 (0.38) | — | |
| SCHEMBL16796843 | 0.62 | DDB1 (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3584879 | 0.62 | DDB1 (0.52) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750885-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |
| EP-2687528-A1 | Fused triazole derivatives as gamma secretase modulators | ARES TRADING S.A. (CH) | 2014-01-22 | — | — | EP | disclosed |