SCHEMBL15435820

SCHEMBL15435820

Cc1ccc(N(c2cc(C)cc(C)c2)c2cc3c4ccccc4c(N(c4ccc(C)cc4)c4cc(C)cc(C)c4)cc3c3ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CYP2C19 P33261 2/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2A6 P11509 1/20 0.32
APP P05067 1/20 0.32
TSPO P30536 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74544 0.93 TSHR (0.38) ALDH1A1CYP2C19TSHRCYP1A2CYP2A6
SCHEMBL29556501 0.93 TSHR (0.38) ALDH1A1CYP2C19TSHRCYP1A2CYP2A6
SCHEMBL2537214 0.93 CYP1A2 (0.36) CYP1A2CYP2A6TSPOKEAP1NFE2L2
SCHEMBL12903366 0.90 APP (0.30) APP
SCHEMBL24010998 0.89 CYP2C19 (0.39) ALDH1A1CYP2C19TSHRCYP1A2APP
SCHEMBL29555095 0.89 CYP2C19 (0.39) ALDH1A1CYP2C19TSHRCYP1A2APP
SCHEMBL25700478 0.89 CYP2C19 (0.39) ALDH1A1CYP2C19TSHRCYP1A2APP
SCHEMBL2535341 0.89 CYP2C19 (0.39) ALDH1A1CYP2C19TSHRCYP1A2APP
SCHEMBL13774333 0.89 CYP2C19 (0.39) ALDH1A1CYP2C19TSHRCYP1A2APP
SCHEMBL12120997 0.88 CYP1A2 (0.37) ALDH1A1CYP2C19CYP1A2CYP2A6APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed