SCHEMBL74544

SCHEMBL74544

Cc1ccc(N(c2ccc(C)cc2)c2cc3c4ccccc4c(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C19 P33261 1/20 0.37
ACHE P22303 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
KIF11 P52732 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2A6 P11509 2/20 0.32
CYP1A2 P05177 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556501 1.00 TSHR (0.38) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL29555095 0.96 CYP2C19 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL25700478 0.96 CYP2C19 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL13774333 0.96 CYP2C19 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL2535341 0.96 CYP2C19 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL24010998 0.96 CYP2C19 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL17933061 0.93 GAA (0.35) TSHRALDH1A1CYP2C19KIF11KEAP1
SCHEMBL15435820 0.93 ALDH1A1 (0.33) TSHRALDH1A1CYP2C19KIF11KEAP1
SCHEMBL13024042 0.91 ALDH1A1 (0.43) TSHRALDH1A1CYP2C19KIF11MEN1
SCHEMBL12238153 0.91 MEN1 (0.37) ALDH1A1CYP2C19ACHEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11711970-B2 Organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-07-25 US disclosed
US-11711970-B2 Organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-07-25 US disclosed
US-11653565-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-16 US disclosed
US-20070167654-A1 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-07-19 US disclosed
US-20070167654-A1 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2007-07-19 US disclosed
US-20070155991-A1 Material for organic electroluminescent device and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2007-07-05 US disclosed
US-20070155991-A1 Material for organic electroluminescent device and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2007-07-05 US disclosed
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-28 US disclosed
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-28 US disclosed
US-20070111028-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 US disclosed
US-20070111028-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-17 US disclosed
US-20070075635-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-04-05 US disclosed
US-20070075635-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC TSHR 4627/4885ALDH1A1 2787/4885CYP2C19 2134/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR TSHR 494/4885ALDH1A1 2290/4885CYP2C19 32/4885
US-11653565-B2 Polycyclic aromatic compound ETV6, EBPL, EML4 TSHR 4531/4885ALDH1A1 3566/4885CYP2C19 2524/4885
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same ALK, ALKBH3, ACVRL1 TSHR 2318/4885ALDH1A1 177/4885CYP2C19 359/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 TSHR 4594/4885ALDH1A1 3052/4885CYP2C19 987/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 TSHR 4594/4885ALDH1A1 3052/4885CYP2C19 987/4885
US-20070145888-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, TYR, ALKBH3 TSHR 4410/4885ALDH1A1 692/4885CYP2C19 1679/4885
US-20070111028-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, TYR, OCIAD2 TSHR 4061/4885ALDH1A1 884/4885CYP2C19 1131/4885
US-11711970-B2 Organic electroluminescent device LEF1, AOC2, AFF2 TSHR 4449/4885ALDH1A1 232/4885CYP2C19 586/4885
US-20070155991-A1 Material for organic electroluminescent device and organic electroluminescent device using same CD99, EML4, L1CAM TSHR 4667/4885ALDH1A1 1095/4885CYP2C19 1809/4885
US-20070167654-A1 Aromatic amine derivative and organic electroluminescence device employing the same TYR, DDC, MAOA TSHR 4013/4885ALDH1A1 315/4885CYP2C19 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.