SCHEMBL15435976

SCHEMBL15435976

c1ccc(-n2c3ccccc3c3c(-c4cccc5c4c4ccccc4n5-c4cccc(-n5c6ccccc6c6ccccc65)c4)cccc32)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
KDM4E B2RXH2 1/20 0.62
ATM Q13315 1/20 0.62
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
JAK2 O60674 1/20 0.38
JAK3 P52333 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38
BRCA1 P38398 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK8 P45983 2/20 0.36
IL1R1 P14778 1/20 0.36
MAPK1 P28482 1/20 0.36
HDAC4 P56524 1/20 0.36
PGR P06401 1/20 0.36
MAPK9 P45984 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998228 0.96 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL11998218 0.93 L3MBTL1 (0.65) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL15435951 0.92 KDM4E (0.53) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL11998190 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL11998191 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL24722554 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL25516393 0.92 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL11998185 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL18561901 0.91 L3MBTL1 (0.63) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL10027608 0.89 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed