Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797488 | 0.78 | PDE10A (0.35) | — | |
| SCHEMBL30524891 | 0.75 | GRM5 (0.36) | GRM5 | |
| SCHEMBL13352184 | 0.74 | NNMT (0.32) | GRM5 | |
| SCHEMBL13352183 | 0.74 | NNMT (0.32) | GRM5 | |
| SCHEMBL14305624 | 0.74 | AKR1B1 (0.38) | — | |
| SCHEMBL858890 | 0.72 | GRM5 (0.54) | GRM5 | |
| SCHEMBL2837929 | 0.70 | GRM5 (0.44) | GRM5 | |
| SCHEMBL2839578 | 0.70 | ALK (0.31) | GRM5 | |
| SCHEMBL13199674 | 0.69 | HTR2A (0.39) | — | |
| SCHEMBL31034411 | 0.69 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687533-A2 | Acrylamide derivatives as FAB I inhibitors | Affinium Pharmaceuticals, Inc. (CA) | 2014-01-22 | — | — | EP | disclosed |