Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21566380 | 0.88 | L3MBTL1 (0.49) | KDM4EATML3MBTL1MAOAACHE | |
| SCHEMBL18086287 | 0.85 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MAOAACHE | |
| SCHEMBL26329938 | 0.85 | KDM4E (0.47) | TOP2AKDM4EATML3MBTL1MAOA | |
| SCHEMBL26329939 | 0.85 | KDM4E (0.47) | TOP2AKDM4EATML3MBTL1MAOA | |
| SCHEMBL26472300 | 0.84 | L3MBTL1 (0.44) | KDM4EATML3MBTL1HTTPOLB | |
| SCHEMBL26329916 | 0.83 | KDM4E (0.43) | TOP2AKDM4EATML3MBTL1MAOA | |
| SCHEMBL26329911 | 0.83 | KDM4E (0.43) | TOP2AKDM4EATML3MBTL1MAOA | |
| SCHEMBL26329936 | 0.83 | KDM4E (0.43) | TOP2AKDM4EATML3MBTL1MAOA | |
| SCHEMBL19769614 | 0.82 | KDM4E (0.40) | KDM4EATML3MBTL1MAOAACHE | |
| SCHEMBL19769677 | 0.82 | KDM4E (0.42) | KDM4EATML3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |