Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30619487 | 0.77 | NR1H2 (0.64) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL20376188 | 0.77 | DYRK1A (0.49) | BRD4 | |
| SCHEMBL4163083 | 0.74 | CAMKK2 (0.47) | BRD4 | |
| SCHEMBL30774427 | 0.73 | NR1H2 (0.49) | NR1H2NR1H3BRD4CREBBPCA12 | |
| SCHEMBL12346330 | 0.73 | NR1H2 (0.48) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL28196805 | 0.73 | NR1H2 (0.59) | NR1H2NR1H3BRD4CREBBPCA12 | |
| SCHEMBL28578718 | 0.73 | NR1H2 (0.69) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL14367891 | 0.72 | NR1H2 (0.75) | NR1H2NR1H3 | |
| SCHEMBL2875418 | 0.72 | NR1H2 (0.51) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL5828628 | 0.72 | PIM1 (0.48) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |