Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 7/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357430 | 0.96 | KDM4E (0.43) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL26329921 | 0.95 | KDM4E (0.42) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL26329910 | 0.95 | KDM4E (0.42) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL26329919 | 0.91 | ALDH1A1 (0.40) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL26329928 | 0.91 | ALDH1A1 (0.40) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL26329743 | 0.89 | KDM4E (0.44) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL15436333 | 0.89 | KDM4E (0.46) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL25847041 | 0.89 | KDM4E (0.53) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL15436426 | 0.89 | FEN1 (0.46) | KDM4EATML3MBTL1FEN1ALDH1A1 | |
| SCHEMBL18357407 | 0.88 | KDM4E (0.39) | KDM4EATML3MBTL1FEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |