Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177682 | 0.67 | CDC25B (0.54) | CDC25BTP53IDO1MEN1USP2 | |
| SCHEMBL11091232 | 0.66 | DHODH (0.44) | CDC25BTP53IDO1MEN1USP2 | |
| Juglone SCHEMBL34185 | 0.65 | MAPT (1.00) | CDC25BTP53IDO1MEN1USP2 | |
| SCHEMBL5299235 | 0.65 | CDC25B (0.58) | CDC25BTP53IDO1MEN1USP2 | |
| Juglone SCHEMBL9280529 | 0.65 | MAPT (1.00) | CDC25BTP53IDO1MEN1USP2 | |
| SCHEMBL30695845 | 0.65 | CDC25B (0.58) | CDC25BTP53IDO1MEN1USP2 | |
| Juglone SCHEMBL29500185 | 0.65 | MAPT (1.00) | CDC25BTP53IDO1MEN1USP2 | |
| SCHEMBL3981996 | 0.64 | KDM4E (0.31) | TP53IDO1MEN1USP2ALDH1A1 | |
| Juglone SCHEMBL14246054 | 0.62 | MAPT (0.92) | CDC25BTP53IDO1MEN1USP2 | |
| SCHEMBL8376967 | 0.62 | ELANE (0.52) | CDC25BTP53IDO1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877455-B1 | FUSED QUINONIC COMPOUNDS | CT ATLANTICO DEL MEDICAMENTO S A CEAMED S A (ES) | 2016-08-17 | — | — | EP | disclosed |
| US-20150175585-A1 | FUSED QUINONIC COMPOUNDS | CENTRO ATLANTICO DEL MEDICAMENTO S.A (CEAMED S.A.) (ES) | 2015-06-25 | — | — | US | disclosed |
| EP-2877455-A1 | FUSED QUINONIC COMPOUNDS | Centro Atlantico del Medicamento S.A (Ceamed, S.A) (ES) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014016314-A1 | FUSED QUINONIC COMPOUNDS | CENTRO ATLANTICO DEL MEDICAMENTO S.A (CEAMED, S.A) (ES) | 2014-01-30 | — | — | WO | disclosed |
| EP-2690094-A1 | Fused quinonic compounds | Centro Atlantico del Medicamento S.A (Ceamed, S.A) (ES) | 2014-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175585-A1 | FUSED QUINONIC COMPOUNDS | STAT3, STAT1, JAK2 | CDC25B 507/4885TP53 73/4885IDO1 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.