Juglone

Juglone

SCHEMBL29500185

O=C1C=CC(=O)c2c(O)cccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
CDC25B P30305 4/20 1.00
AURKA O14965 4/20 1.00
KDM4E B2RXH2 4/20 1.00
RECQL P46063 4/20 1.00
KMT2A Q03164 4/20 1.00
AURKB Q96GD4 3/20 1.00
ALDH1A1 P00352 3/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
HSD17B10 Q99714 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 3/20 1.00
P4HB P07237 3/20 1.00
TOP1 P11387 3/20 1.00
TRPA1 O75762 2/20 1.00
TP53 P04637 2/20 1.00
CYP3A4 P08684 2/20 1.00
CASP1 P29466 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juglone SCHEMBL34185 1.00 MAPT (1.00) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL9280529 1.00 MAPT (1.00) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL17888856 0.98 MAPT (0.96) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL14246054 0.96 MAPT (0.92) MAPTCDC25BAURKAKDM4ERECQL
Anthraquinone SCHEMBL14245036 0.92 MAPT (0.85) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL9476381 0.92 MAPT (0.85) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL27828137 0.92 MAPT (0.85) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL2720570 0.92 MAPT (0.85) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL25330089 0.90 MAPT (0.81) MAPTCDC25BAURKAKDM4ERECQL
Juglone SCHEMBL11781111 0.90 MAPT (0.81) MAPTCDC25BAURKAKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119791112-A Application of naphthoquinone compound in preparation of nematode prevention and control medicament 贵州大学 2025-04-11 CN claimed
CN-119744184-A Mussel inspired tissue adhesives and methods of use thereof 普渡研究基金会 2025-04-01 CN claimed
CN-119500075-A Preparation method of formaldehyde adsorption antibacterial material with activated carbon as carrier 河南工程学院 2025-02-25 CN claimed
CN-119100942-A Juglone-amino acid ester derivative, synthesis method thereof and application thereof in biological antibacterial agent 江苏科技大学 2024-12-10 CN claimed
CN-117844484-A Selective etching solution for aluminum oxide and IGZO 湖北兴福电子材料股份有限公司 2024-04-09 CN claimed
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN claimed
CN-115703697-A Novel organic alkoxide agglomerate and preparation method and application thereof 上海科技大学 2023-02-17 CN claimed
WO-2023016459-A1 NOVEL ORGANIC ALKOXIDE AGGLOMERATE, AND PREPARATION METHOD THEREFOR AND APPLICATION AND THEREOF 上海科技大学 2023-02-16 WO claimed
CN-115697956-A Preparation method of quinone compound 上海科技大学 2023-02-03 CN claimed
CN-113735696-B Preparation method of quinone compound 上海科技大学 2022-11-08 CN claimed
CN-115209732-A Agent for controlling plant diseases and special use thereof in treatment of plants infected with xylem-fastidious bacteria 维氏化学有限责任公司 2022-10-18 CN claimed
EP-4739717-A2 PREPARATION OF A HIGH REACTION TEMPERATURE DPAM HAVING IMPROVED STANDARD VISCOSITY AND WATER SOLUBILITY KEMIRA OYJ (FI) 2026-05-13 EP disclosed
CN-122012305-A Pseudomonas putida (Pseudomonas putida) RT12 and application thereof 新疆林科院经济林研究所 2026-05-12 CN disclosed
US-12568964-B2 Phytosanitary agent and its particular use in the treatment of plants infected by Xylella fastidiosa Vextachem S.R.L. (IT) 2026-03-10 US disclosed
EP-4601469-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR INCREASED PLANT QUALITY RDX-N, LLC (US) 2025-08-20 EP disclosed
CN-114642637-A Pure naphthoquinone compound nano particle and preparation method of carrier-free surfactant-free nano particle 吉林大学 2022-06-21 CN disclosed
CN-109310648-B Compositions comprising cannabidiol and a second therapeutic agent for treating cancer 杰伊制药公司 2022-06-03 CN disclosed
WO-2022091123-A1 5-HYDROXY-1,4-NAPHTHALENEDIONE FOR USE IN THE TREATMENT OF CANCER GODAVARI BIOREFINERIES LIMITED (IN) 2022-05-05 WO disclosed
WO-2022091123-A1 5-HYDROXY-1,4-NAPHTHALENEDIONE FOR USE IN THE TREATMENT OF CANCER GODAVARI BIOREFINERIES LIMITED (IN) 2022-05-05 WO disclosed
CN-114206300-A Preventing and reducing keratinization disorder and related cosmetic 默克专利股份有限公司 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568964-B2 Phytosanitary agent and its particular use in the treatment of plants infected by Xylella fastidiosa MT-CO2, SOD1, MT-CO1 MAPT 1996/4885CDC25B 1311/4885AURKA 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.