Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651744 | 0.96 | GAA (0.60) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL11668133 | 0.94 | GAA (0.55) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL5412953 | 0.90 | GAA (0.56) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL13006817 | 0.89 | GAA (0.50) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL2612492 | 0.85 | GAA (0.51) | GAATSHRALDH1A1CYP3A4KMT2A | |
| SCHEMBL2265057 | 0.84 | GAA (0.55) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL11308351 | 0.84 | GAA (0.49) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL11653541 | 0.83 | ALDH1A1 (0.50) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL2612497 | 0.82 | GAA (0.44) | GAATSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL27881180 | 0.82 | GAA (0.44) | GAATSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9168710-B2 | Motor-vehicle top | PARAT BETEILIGUNGS GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20140028048-A1 | MOTOR-VEHICLE TOP | PARAT TECHNOLOGY GROUP GMBH (DE) | 2014-01-30 | — | — | US | disclosed |