SCHEMBL15439202

SCHEMBL15439202

C/C(=N\N(Cc1ccccc1)[Si](C)(C)C)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.47
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
GAA P10253 2/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439205 1.00 G6PC1 (0.47) G6PC1MEN1KMT2ACES2CES1
SCHEMBL15440188 0.86 G6PC1 (0.44) G6PC1MEN1KMT2AGAANPC1
SCHEMBL15440191 0.86 G6PC1 (0.44) G6PC1MEN1KMT2AGAANPC1
SCHEMBL14799828 0.85 G6PC1 (0.49) G6PC1MEN1KMT2AGAANPC1
SCHEMBL14799829 0.85 G6PC1 (0.49) G6PC1MEN1KMT2AGAANPC1
SCHEMBL15439367 0.85 G6PC1 (0.44) G6PC1MEN1KMT2ACES2CES1
SCHEMBL15439369 0.85 G6PC1 (0.44) G6PC1MEN1KMT2ACES2CES1
SCHEMBL15440223 0.83 G6PC1 (0.65) G6PC1MEN1KMT2ACES2CES1
SCHEMBL15440224 0.83 G6PC1 (0.65) G6PC1MEN1KMT2ACES2CES1
SCHEMBL15440366 0.82 G6PC1 (0.47) G6PC1MEN1KMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed