Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439476 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15439675 | 0.86 | NPC1 (0.46) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15439678 | 0.86 | NPC1 (0.46) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440243 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15439257 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440242 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440283 | 0.84 | G6PC1 (0.53) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440284 | 0.84 | G6PC1 (0.53) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440250 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL15440046 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |