SCHEMBL15439574

SCHEMBL15439574

CN(C)/N=C(/CCC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
NR4A2 P43354 1/20 0.53
ALDH1A1 P00352 5/20 0.49
GAA P10253 1/20 0.49
CYP2C19 P33261 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
MAPT P10636 3/20 0.48
LMNA P02545 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
MAPK1 P28482 3/20 0.46
CTNNB1 P35222 2/20 0.46
WNT3A P56704 2/20 0.46
USP2 O75604 2/20 0.46
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HDAC1 Q13547 2/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439577 1.00 KMT2A (0.56) KMT2ANR4A2ALDH1A1GAACYP2C19
SCHEMBL15439291 0.90 L3MBTL1 (0.55) KMT2ANR4A2ALDH1A1GAACYP2C19
SCHEMBL15439289 0.90 L3MBTL1 (0.55) KMT2ANR4A2ALDH1A1GAACYP2C19
SCHEMBL14799525 0.89 ATM (0.48) KMT2AALDH1A1GAAL3MBTL1MAPT
SCHEMBL14799523 0.89 ATM (0.48) KMT2AALDH1A1GAAL3MBTL1MAPT
SCHEMBL15440037 0.86 KMT2A (0.43) KMT2AALDH1A1GAAL3MBTL1MAPT
SCHEMBL15440036 0.86 KMT2A (0.43) KMT2AALDH1A1GAAL3MBTL1MAPT
SCHEMBL15439325 0.84 KMT2A (0.50) KMT2ANR4A2ALDH1A1GAACYP2C19
SCHEMBL15439326 0.84 KMT2A (0.50) KMT2ANR4A2ALDH1A1GAACYP2C19
SCHEMBL15439541 0.84 KMT2A (0.50) KMT2ANR4A2ALDH1A1GAACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed