Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439704 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15440127 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15440128 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15440267 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15440265 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15439633 | 0.77 | — | — | |
| SCHEMBL15439023 | 0.77 | — | — | |
| SCHEMBL15439559 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15440553 | 0.74 | GAA (0.43) | ALDH1A1ALOX15GAAMAPTKMT2A | |
| SCHEMBL15439420 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ALOX15GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |