SCHEMBL15440232

SCHEMBL15440232

C[SiH](C)N(Cc1ccccc1)N=C1CCCC(=O)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.41
CA2 P00918 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 3/20 0.33
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
BRD4 O60885 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15440176 0.89 MAPT (0.40) G6PC1CA2LMNAMAPTGAA
SCHEMBL15438795 0.88 G6PC1 (0.40) G6PC1CA2LMNAMAPTMAOA
SCHEMBL15439463 0.82 G6PC1 (0.43) G6PC1CA2LMNAMAPTMAOA
SCHEMBL15439462 0.82 G6PC1 (0.43) G6PC1CA2LMNAMAPTMAOA
SCHEMBL15440518 0.81 G6PC1 (0.60) G6PC1CA2LMNAMAPTMAOA
SCHEMBL15440517 0.81 G6PC1 (0.60) G6PC1CA2LMNAMAPTMAOA
SCHEMBL15438614 0.81 G6PC1 (0.33) G6PC1CA2MAOBGAARAB9A
SCHEMBL15439643 0.80 MAOB (0.34) G6PC1CA2MAOBRAB9AALDH1A1
SCHEMBL15439854 0.78 MEN1 (0.37) G6PC1CA2LMNAMAPTMAOB
SCHEMBL15439627 0.78 G6PC1 (0.41) G6PC1CA2LMNAMAPTMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed