SCHEMBL15440251

SCHEMBL15440251

CC(=O)CC/C(C)=N/N(C)C

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.42
SLC15A2 Q16348 1/20 0.42
CHRM1 P11229 1/20 0.35
HTT P42858 1/20 0.32
PAOX Q6QHF9 2/20 0.31
ACHE P22303 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15440252 1.00 ALDH1A1 (0.50) ALDH1A1LMNASLC15A2CHRM1HTT
SCHEMBL14799681 0.87 ALDH1A1 (0.42) ALDH1A1
SCHEMBL15438809 0.78 ALDH1A1 (0.42) ALDH1A1LMNASLC15A2CHRM1
SCHEMBL15440031 0.78 ALDH1A1 (0.42) ALDH1A1LMNASLC15A2CHRM1
SCHEMBL15439391 0.77 HTT (0.50) ALDH1A1HTTTDP1
SCHEMBL15439392 0.77 HTT (0.50) ALDH1A1HTTTDP1
SCHEMBL15439117 0.75 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2
SCHEMBL15439341 0.75 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2
SCHEMBL15439118 0.75 ALDH1A1 (0.43) ALDH1A1LMNASLC15A2
SCHEMBL19044211 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed