SCHEMBL15440264

SCHEMBL15440264

C[Si](C)(C)N(N=C1CCCCC1=O)[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15440263 1.00 ALDH1A1 (0.33) ALDH1A1GAAMAPT
SCHEMBL16492418 0.84
SCHEMBL16492417 0.84
SCHEMBL15440201 0.84 TP53 (0.32)
SCHEMBL15440200 0.84 TP53 (0.32)
SCHEMBL15440102 0.82 TP53 (0.31)
SCHEMBL15440104 0.82 TP53 (0.31)
SCHEMBL15439319 0.82 ALDH1A1 (0.33) ALDH1A1GAAMAPT
SCHEMBL15439317 0.82 ALDH1A1 (0.33) ALDH1A1GAAMAPT
SCHEMBL15438850 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed