SCHEMBL15440274

SCHEMBL15440274

O=Cc1cccc(C=NN(Cc2ccccc2)Cc2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 16/20 0.70
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
KMT2A Q03164 1/20 0.49
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15440272 1.00 G6PC1 (0.70) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL14799388 0.92 G6PC1 (0.82) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL14799390 0.92 G6PC1 (0.82) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL15439683 0.85 G6PC1 (0.77) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL15439687 0.85 G6PC1 (0.77) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL15440153 0.85 G6PC1 (0.50) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL15440151 0.85 G6PC1 (0.50) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL8499080 0.83 G6PC1 (1.00) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL8495011 0.83 G6PC1 (1.00) G6PC1MAPTMEN1LMNAKMT2A
SCHEMBL15439222 0.81 G6PC1 (0.47) G6PC1MAPTMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed