Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440348 | 1.00 | G6PC1 (0.40) | G6PC1TSHRHTTLMNAMAPT | |
| SCHEMBL14799604 | 0.90 | G6PC1 (0.44) | G6PC1TSHRALDH1A1CYP2C19CA2 | |
| SCHEMBL16492431 | 0.90 | G6PC1 (0.44) | G6PC1TSHRALDH1A1CYP2C19CA2 | |
| SCHEMBL15439627 | 0.88 | G6PC1 (0.41) | G6PC1TSHRHTTLMNAMAPT | |
| SCHEMBL15439628 | 0.88 | G6PC1 (0.41) | G6PC1TSHRHTTLMNAMAPT | |
| SCHEMBL15439473 | 0.88 | MAPT (0.40) | G6PC1TSHRHTTLMNAMAPT | |
| SCHEMBL15439475 | 0.88 | MAPT (0.40) | G6PC1TSHRHTTLMNAMAPT | |
| SCHEMBL14799342 | 0.83 | G6PC1 (0.44) | G6PC1TSHRALDH1A1CYP2C19CA2 | |
| SCHEMBL14799345 | 0.83 | G6PC1 (0.44) | G6PC1TSHRALDH1A1CYP2C19CA2 | |
| SCHEMBL15439791 | 0.80 | G6PC1 (0.43) | G6PC1TSHRHTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |